Already in 1831, there were a few homeopaths who were using combinations of
two homeopathic remedies. At that time Hahnemann showed vivid interest in this
new development, but he did not get involved very much himself.
In 1860, Arthur Lutze (18131870) wrote about the success of treating patients
with two combined remedies in his homeopathic textbooks. By the way, it was the
Central Homeopathic Dispensary of Dr. Willmar Schwabe, where he obtained the
homeopathic substances for his mixtures.
But it was not until 1890 when Emanuel Felke (18561926) combined several
homeopathic remedies into one complex medicine. These complex medicines were
assigned to certain diseases or organ systems.
Finally, Professor Emil Bürgi (18721947) a pharmacologist in Bern, Switzerland,
established the theoretic fundamentals on the effects of complex medicines. He
stated that two or more remedies with the same effect on a biological system,
but different points of action on that system increase their effect
synergistically when combined.
Dr. Willmar Schwabe Pharmaceuticals provided a series of complex medicines
already in 1925. By 1940 Schwabe Pharmaceuticals provided its own complex
medicines, each combining five single remedies in low potencies; and in 1960,
Schwabe Pharmaceuticals presented for the first time a series of socalled
Pentarkan complex medicines to the international market, result of many years of
cooperation and experience shared with homeopathic experts. This line has been
developed according to the motto: as many single remedies as necessary and as
few as possible.
Each Pentarkan is a combination of two up to five wellproven homeopathic single
remedies selected to form a synergistic product for specific indications. Here,
the single remedies, i.e. the active substances are present in low potencies to
guarantee an organspecific effect in the respective indication. The
preparations´ claims of indication result from the respective homeopathic drug
pictures and the clinical application of the active substances. Each active
substance is a proven reasonable part of the combination as it contributes to
the positive appraisal of the finished product enhancing the synergistic effect
with regard to the indication. The basis of this evaluation is the homeopathic
literature in general, specifically the Materiae Medicae, providing descriptions
of the single remedies, their field of action, the symptoms reported in drug
provings and their clinical application, and the monographs of the Commission D,
an expert group who reviewed the national and international scientific
literature with regard to safety and effectiveness of homeopathic single
remedies for the German Health authorities, today known as the Federal Institute
for Drugs and Medical Devices. These monographs are still the legal fundament
for the registration of homeopathic medicinal products in Germany.
Many years of cooperation with experienced homeopaths have produced a wide range
of Pentarkan medicines. They cover the most frequent indications that have to be
treated in every day medical practice.
All in all, there are Pentarkan preparations that can be used in various medical
fields such as dermatology, gastroenterology, gynaecology, cardiology
(cardiovascular complaints) and circulation diseases, otolaryngology, neurology,
orthopaedics, urology and paediatrics.
Therapy by complex medicines saves the otherwise timeconsuming search for the
appropriate individual homeopathic single remedy. They are a convenient option
both for the qualified therapist to allow an indicationspecific treatment of
complaints, and for the patient for a reasonable and readytouse alternative
for selfmedication in everyday complaints.
Besides the Pentarkan line, Schwabe Pharmaceuticals also provides socalled
specialties which are also complex medicines. Like the Pentarkans they cover a
series of common indications. For further information see the product
information leaflets
Product Name  Compositions  Indications 
Aconitum Pentarkan® Ptk. 2 

1 tablet contains: Aconitum 3X 25 mg; Belladonna 3X 25 mg; Bryonia 3X 25 mg; Ferrum phosphoricum 2X 25 mg; Gelsemium 3X 25 mg; Excipients Q.S. to 250 mg.  Traditionally used for the treatment of acute feverish infections of
the respiratory tract. 

Aesculus Pentarkan® Ptk. 3 

100 g contain: Aesculus 1X 30 g; Calcium fluoratum 6X 10 g; Arnica 2X 10 g; Carduus marianus 1X 10 g; Collinsonia canadensis 1X 10 g; Excipients Q.S. to 100 g. Ethanol 60 % (V/V).  Traditionally used for the treatment of varicose veins; such as
piles. 

Asa foetida Pentarkan® Ptk. 12 

100 g contain: Asa foetida 2X 10 g; Ignatia 3X 10 g; Nux moschata 3X 10 g; Zincum valerianicum 5X 10 g; Leonurus cardiaca 1X 10 g; Excipients Q.S. to 100 g. Ethanol 68 % (V/V).  Traditionally used for the treatment of nervous dysfunctions of the
digestive organs or cardiovascular system; nervous exhaustion and
anxiety or stressrelated conditions. 

Aurum jodatum Pentarkan® Ptk. 13 

1 tablet contains: Aurum jodatum 3X 25 mg; Barium carbonicum 3X 25 mg; Calcium fluoratum 3X 25 mg; Arnica 2X 25 mg; Excipients Q.S. to 250 mg.  Traditionally used for the treatment of complaints caused by
arteriosclerosis. 

Berberis Pentarkan® Ptk. 15 

1 tablet contains: Berberis Ø 25 mg; Lycopodium 2X 25 mg; Urtica Ø 50 mg; Excipients Q.S. to 250 mg.  Traditionally used for the treatment of gout and complaints caused
by goutrelated kidney stone formation. 

Bismutum Pentarkan® Ptk. 16 

1 tablet contains: Bismutum subnitricum 2X 25 mg; Capsicum 5X 25 mg; Robinia pseudacacia 5X 25 mg; Iris 3X 25 mg; Arsenicum album 5X 25 mg; Excipients Q.S. to 250 mg.  Traditionally used for the treatment of gastric hyperacidity (too
much acid in the stomach) associated with heartburn; ructus (belching)
and stomachache. 

Carbo vegetabilis Pentarkan® Ptk. 22 

Carbo vegetabilis Pentarkan® Ptk. 22 
Traditionally used for the treatment of meteorism (flatulency). 

Carduus marianus Pentarkan® Ptk. 23 

100 g contain: Acidum hydrofluoricum 5X 10 g; Aurum chloratum 4X 10 g; Carduus marianus Ø 30 g; Quassia amara Ø 10 g; Excipients Q.S. to 100 g. Ethanol 46 % (V/V).  Traditionally used to accompany individual treatment of chronic
liver disease. 

Cinnabaris Pentarkan® Ptk. 31 

1 tablet contains: Cinnabaris 3X 25 mg; Hydrastis 3X 25 mg; Kalium bichromicum 3X 25 mg; Echinacea 1X 25 mg; Excipients Q.S. to 250 mg.  Traditionally used for the treatment of acute and chronic sinusitis.


Damiana Pentarkan® Ptk. 40 

100 g contain: Acidum phosphoricum 2X 10 g; Ambra 3X 10 g; Damiana Ø 30 g;  Traditionally used for the treatment of conditions involving nervous
exhaustion; including neurasthenia; poor libido and impotence. 

Echinacea Pentarkan® Ptk. 42 

100 g contain: Echinacea purpurea Ø 30 g; Lachesis 9X 10 g; Mercurius solubilis Hahnemanni 8X 10 g; Thuja 1X 10 g; Phytolacca 4X 10 g; Excipients Q.S. to 100 g. Ethanol 62 % (V/V).  Traditionally used to treat inflammation of the mucous membranes;
e.g. infections of the respiratory or urinary tract; and to boost the
body’s resistance. 

Eupatorium Pentarkan® Ptk. 43 

100 g contain: Eupatorium perfoliatum Ø 20 g; Eucalyptus 2X 10 g; Dulcamara 1X 10 g; Gelsemium 3X 10 g; Phosphorus 5X 10 g; Excipients Q.S. to 100 g. Ethanol 65 % (V/V).  Traditionally used for the treatment of flulike infections. 

Ferrum Pentarkan® Ptk. 45 

1 tablet contains: Ferrum metallicum 2X 25 mg; Chininum arsenicosum 5X 25 mg; Manganum aceticum 5X 25 mg; Acidum phosphoricum 1X 2.5 mg; Excipients Q.S. to 250 mg.  Traditionally used for the treatment of debility (feelings of
weakness). 

Gnaphalium Pentarkan® Ptk. 49 

100 g contain: Gnaphalium polycephalum 1X 10 g; Phytolacca 1X 10 g; Aconitum 3X 10 g; Dulcamara 2X 10 g; Rhus toxicodendron 3X 10 g; Excipients Q.S. to 100 g. Ethanol 55 % (V/V).  Traditionally used for the treatment of pain conditions associated
with sciatica (lumbar sciatica). 

Graphites Pentarkan® Ptk. 50 

1 tablet contains: Graphites 3X 25 mg; Sulfur 4X 25 mg; Mercurius solubilis Hahnemanni 8X 25 mg; Causticum Hahnemanni 3X 25 mg; Arsenicum album 5X 25 mg; Excipients Q.S. to 250 mg.  Traditionally used for the treatment of eczema.  
Grindelia Pentarkan® Ptk. 51 

100 g contain: Ephedra vulgaris Ø 30 g; Grindelia robusta Ø 3 g; Ipecacuanha 3X 10 g; Justica adhatoda 1X 10 g; Lobelia inflata 3X 10 g; Excipients Q.S. to 100 g. Ethanol 66 % (V/V).  Traditionally used for the treatment of bronchial asthma. 

Magnesium phosphoricum Pentarkan® Ptk. 60 

1 tablet contains: Magnesium phosphoricum 2X 25 mg; Chamomilla 2X 25 mg; Colocynthis 3X 25 mg; Potentilla anserina Ø 100 mg; Aesculus 1X 25 mg; Excipients Q.S. to 250 mg.  Traditionally used in painful menstrual bleeding (functional
dysmenorrhoea). 

Nux vomica Pentarkan® Ptk. 63 

100 g contain: Anacardium 4X 10 g; Arsenicum album 5X 10 g; Centaurium erythraea e planta tota recente 1X 10 g; Leonurus cardiaca 1X 10 g; Nux vomica 3X 10 g; Excipients Q.S. to 100 g. Ethanol 58 % (V/V).  Traditionally used for the treatment of stomach complaints; such as gastritis.  
Passiflora Pentarkan® Ptk. 66 

100 g contain: Passiflora incarnata Ø 30 g; Zincum metallicum 6X 1 g; Lupulus Ø 30 g; Eschscholzia californica ex herba flor. rec. Ø 25 g; Excipients Q.S. to 100 g. Ethanol 64 % (V/V).  Traditionally used in insomnia (difficulty in falling asleep and/or
maintaining sleep) due to nervous tension. 

Rhus toxicodendron Pentarkan® Ptk. 73 

100 g contain: Rhus toxicodendron 3X 10 g; Bryonia 1X 10 g; Spiraea ulmaria Ø 30 g; Cimicifuga 2X 10 g; Urtica 1X 10 g; Excipients Q.S. to 100 g. Ethanol 62 % (V/V).  Traditionally used for the treatment of musculoskeletal diseases;
such as muscular rheumatism. 

Sabal Pentarkan® Ptk. 75 

100 g contain: Sabal serrulatum Ø 40 g; Echinacea purpurea Ø 30 g; Cantharis 4X 10 g; Mercurius bijodatus 8X 10 g; Excipients Q.S. to 100 g. Ethanol 63 % (V/V).  Traditionally used to treat inflammation of the prostate gland and
bladder. 

Senega Pentarkan® Ptk. 77 

1 tablet contains: Senega Ø 125 mg; Antimonium sulfuratum aurantiacum 3X 25 mg; Hepar sulfuris 3X 25 mg; Naphthalinum 4X 25 mg; Stannum jodatum 3X 25 mg; Excipients Q.S. to 250 mg.  Traditionally used for the treatment of chronic bronchitis. 

Solidago Pentarkan® Ptk. 79 

100 g contain: Solidago virgaurea Ø 30 g; Ononis spinosa Ø 30 g; Equisetum hiemale Ø 20 g; Petroselinum 1X 10 g; Excipients Q.S. to 100 g. Ethanol 58% (V/V).  Traditionally used to accompany individual treatment of oedema
caused by kidney diseases. 

Spigelia Pentarkan® Ptk. 81 

100 g contain: Spigelia 3X 10 g; Belladonna 3X 10 g; Glonoinum 5X 10 g; Nux vomica 3X 10 g; Secale cornutum 3X 10 g; Excipients Q.S. to 100 g. Ethanol 70% (V/V).  Traditionally used for the treatment of headache. 

Sticta Pentarkan® Ptk. 82 

100 g contain: Sticta Ø 10 g; Bryonia 2X 10 g; Ipecacuanha 3X 10 g; Rumex 1X 10 g; Spongia 2X 10 g; Excipients Q.S. to 100 g. Ethanol 59% (V/V).  Traditionally used for the treatment of acute bronchitis. 

Urtica Pentarkan® Ptk. 86 

100 g contain: Apis melifica 2X 10 g; Belladonna 3X 10 g; Calcium carbonicum Hahnemanni 6X 1 g; Dulcamara 2X 10 g; Urtica 2X 10 g; Excipients Q.S. to 100 g. Ethanol 55% (V/V).  Traditionally used for the treatment of itchy skin rashes; such as
urticaria. 

Veratrum Pentarkan® Ptk. 87 

100 g contain: Veratrum 3X 10 g; Arsenicum album 5X 10 g; Mercurius sublimatus corrosivus 8X 10 g; Xysmalobium undulatum e radice siccata 2X 20 g; Excipients Q.S. to 100 g. Ethanol 55% (V/V).  Traditionally used for the treatment of diarrhoea.  
Viscum Pentarkan® Ptk. 89 

100 g contain: Viscum album Ø 40 g; Secale cornutum 3X 10 g; Arnica 2X 10 g; Crataegus Ø 1 g; Excipients Q.S. to 100 g. Ethanol 55% (V/V).  Traditionally used to accompany treatment of hypertension (high
blood pressure). 